Compatibility guideShimano 105 R7100 Rear Derailleur vs SRAM Eagle XG-1275 Cassette 10-52CompatibleThese components should work together.Why this verdict• Both parts support 12-speed. Check your own build Start a buildOther pairings for Shimano 105 R7100 Rear DerailleurShimano 105 CS-R7100 Cassette 11-34CassetteCompatibleSRAM NX Eagle PG-1230 CassetteCassetteCompatibleKMC X10 Silver/BlackChainNot compatibleOther pairings for SRAM Eagle XG-1275 Cassette 10-52SRAM GX Eagle Rear DerailleurRear DerailleurCompatibleDT Swiss XR 1700 Spline 29 WheelsetWheelsetNot compatibleKMC X10 Silver/BlackChainNot compatible